Abstract

Aim of the work is to describe the mechanisms of therapeutic effect of platelet-rich plasma (PRP) components on the retina in macular hole (MH) surgery. Methods. This study presents the results of 36 cases of surgical treatment of MH and the use of autologous PRP. Cellular composition of PRP of 24 patients was analyzed. Results. 2 months after the operation, all the patients had restoration of all retinal layers in the MH region and positive dynamics of visual acuity in comparison with preoperative period. After follow-up for 6 months after surgery, no cases of MH relapse were detected. Conclusion. The accumulation of data on the effective use of PRP components makes it possible to plan its wider and more effective use in the treatment of degenerative, infectious, post-traumatic and other disorders of the structures of the eye. Key words: macular hole; platelet-rich plasma.

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