ПРИВЕРЖЕННОСТЬ ЛЕЧЕНИЮ ВИЧ-ИНФИЦИРОВАННЫХ ПАЦИЕНТОВ С ЗАВИСИМОСТЬЮ ОТ ОПИОИДОВ

Abstract

Background. Low commitment in HIV-infected patients with opioid dependence (PHOD) leads to a progression of HIV, its distribution, heavy medical and social consequences. The aim is to study risk factors for poor adherence to treatment in HIV-infected drug users. Material and methods. Study of risk factors for poor adherence to treatment among 213 PHOD. The socio-demographic data of respondents, their attitude to the problem, treatment of combined pathology, the level of awareness of the consequences of HIV infection combined with opioid dependence, the nature of social functioning, criminal activity, risk behavior and the organization of medical care for PHOD. The results. The level of medication adherence associated with the ability of PHOD to critically assess their disease state and its consequences (OR=2,5; 95% CI [1,5-4,1]; p<0.05; χ2=14,7; p<0.001; R=0.2), belief in treatment success (OR=2,5; 95% CI [1,5-4,0]; p<0.05; χ2=14,5; p<0,001; R=0.2), the nature of drug use and effectiveness of ART (OR=5,8; 95% CI [3,5-9,8]; p<0.05; χ2=49,9; p<0.001; R=0.5), the problematic of SF (OR=2,3; 95% CI [1,4-3,7]; p<0.05; χ2=11,4; p<0.001; R=0.2), criminal activity (OR=3,2; 95% CI [1,9-5,1]; p<0.05; χ2=23,4; p<0.001; R=0,1), risky behavior (OR=6,7; 95% CI [3,1-14,5]; p<0.05; χ2=28.5; p<0.001; R=0.3) and organization of medical care (OR=2.2; 95% CI [1.3-3.5]; p<0.05; χ2=9.96; p<0.002; R=0.2). Conclusions. The low level of adherence to treatment in PHOD is associated with a low ability to critically assess the painful condition and its consequences, lack of confidence in the success of treatment, active drug use and low efficiency of ART, problem SF, criminal activity, risky behavior and poor quality of medical care. The knowledge of PHOD about the consequences of combined pathology not so much influenced, but reflected the tendency to influence treatment adherence.