Abstract
The ability of mesenchymal stem cells (MSCs) isolated from the decidua, chorionic tissue and amniotic membrane of the placenta to the self-renewal and the proliferation was investigated. Our results revealed that the number of colony forming unit-fibroblast (CFU-F) and the growth rate of MSCs were higher in the decidua and chorionic tissue compared to the amniotic membrane. Decidua MSCs and chorionic MSCs possessed a similar powerful proliferative potential and increased in 1010- fold in cultures for 3 months, that is 103 times more then the amniotic MSCs. The cumulative population doubling (PD) of placenta-derived MSCs was significantly higher at all passages then PD of bone marrow derived MSCs. The decidua and chorionic tissue of the placenta are ideal MSCs sources for cell based therapy.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
