Abstract

College of Pharmacy, Yonsei University(Received: 25 June 2015 / Accepted: 27 June 2015)Clay minerals have been used in pharmaceutical industries as active ingredients and excipients without pharmaco-logical activity such as diluents, emulsifying agents, viscosity-increasing agents, and lubricants. For example, bento-nite, kaolin, magnesium aluminum silicate, and talc are generally and extensively used pharmaceutical ingredients,which are restrictedly regulated by Pharmacopoeias. We discuss the physicochemical and biopharmaceutical proper-ties of clay minerals. In addition, we introduce the cases of pharmaceutical applications of clay minerals. From thisreview, pharmaceutical applications of clay minerals can be one of strategies for the development of high value-added products from clay minerals.

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