Характеристика аллергического компонента воспалительных инфильтратов при хроническом среднем отите

Abstract

The article presents data characterizing the inflammatory process in the chronic otitis media (COM) from the standpoint of parameters related to the development of the allergic component of inflammatory infiltrates, regardless of the exudate nature. For comparison, cases with acute otitis media (AOM) were taken. They were obtained as a result of histomorphometric study. Both in acute and chronic otitis media, direct and indirect signs of allergic inflammation were revealed. Of particular interest is the significant predominance of eosinophils in the COM group, which may indicate their more important role in the chronic process, including an increase in their number at the wall edge in the microcirculation vessels. Thus, the study results show that in chronic otitis media, the allergic component plays a significant role in the pathogenesis of the inflammatory process. An important factor in this case is the anatomical and physiological relationship of the tissue structures of the middle ear with the Eustachian tube and the nasopharynx. This fact must be taken into account when constructing the treating tactics of chronic otitis media, an important element of which could be the use of drugs not only with anti-inflammatory and immunosuppressive, but also anti-allergic properties, especially of prolonged action, as well as herbal preparations with similar properties.