Abstract
У статті наведено власне клінічне спостереження успішного лікування фульмінантної форми гострого гепатиту В із застосуванням глюкокортикостероїдів та аналогів нуклеозидів. Особливістю клінічного випадку виявився розвиток аспергільозу легень, що потребувало хірургічного лікування. З урахуванням зникнення антигенних маркерів гепатиту В, появи серoконверсії anti-HBs у високому титрі (через 6 та 12 місяців) пацієнтка, як реконвалесцент гострого гепатиту В, була знята з диспансерного обліку.
Highlights
We know that fulminant hepatitis B is a massive immune-mediated lysis of infected hepatocytes, which explains the absence in many patients with severe fulminant hepatitis B virus replication, but risk factors for fulminant form of hepatitis B are almost certain
The literature shows the results of the successful use of antiviral agents in the treatment of patients with fulminant hepatitis B, such as nucleot(s)ide analogs
In article we show the proper clinical follow successful treatment of fulminant form of acute hepatitis B with glucocorticoids and nucleoside analogues
Summary
We know that fulminant hepatitis B is a massive immune-mediated lysis of infected hepatocytes, which explains the absence in many patients with severe fulminant hepatitis B virus replication, but risk factors for fulminant form of hepatitis B are almost certain.
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