Abstract

The aim of the study was to estimate the influence of radio- and chemotherapy and tumor's localization on executive functions of the prefrontal cortex. Research involved 58 children with neuro-oncological disease in anamnesis (cerebellum localization and temporal – parietal lobes localization) treated in the Morozov Children's Clinical Hospital. Also research involved 120 typically developing children. Planning was assessed using the Cambridge planning test (Stockings of Cambridge) computer battery of neuropsychological tests CANTAB (Cambridge Neuropsychological Test Automated Battery). Additionally, it is revealed that there is an adverse effect of chemotherapy and radiotherapy on executive functions in tumor of the cerebellum. Funding This work was supported by grant RFBR № 15-06-08680. Acknowledgements The authors thank neuropsychologist E.Yu. Vlasova and neurologist E.V. Andreeva for help in gathering data.

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