Abstract
Researches on influence of long-term peroral taurine injection on physiological and biochemical blood parameters of rats, as indexes of functional state of animal organism, were carried out. Researches were conducted on male Wistar rats (n=16) that were 4 months old and with weight 140–160 g. Animals were divided into four groups (4 rats in each) – control, animals of which were injected in esophagus daily, once a day drinking water, and three experimental groups that were injected 5 (І experimental group), 10 (ІІ experimental group) та 20 (ІІІ experimental group) mg of taurine/kg of body weight. It was registered, that in II experimental group content of hemoglobin in whole blood and in one erythrocyte was higher than in control group. Also, in rats of II and III experimental groups blood oxygenation speed increased in 1.5 and 2.5 times, and in bllod plasma concentration of glucose decreased on 36.7 та 18.4 %. Content of cholesterol in blood plasma was on control levels, but activity of lactate dehydrogenase in whole blood was higher in all experimental groups. In blood plasma of III experimental group activity of alkaline phosphatase decreased. Activity of aspartate transaminase was on control levels, and de Ritis ratio increased in I and III experimental groups. Role of taurine as oxidative metabolism activator is discussed.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
