ЖАНУАРЛАРДА ҰЙҚЫ БЕЗІ ҚЫЗМЕТІНІҢ БҰЗЫЛУЫ КЕЗІНДЕГІ ҚАН АҒЫСЫНДАҒЫ ӨЗГЕРІСТЕР

Abstract

the article examines the blood supply of tissues and organs during pancreatic disorders, changes in blood flow. When modeling acute pancreatitis, the functions of blood circulation and blood indicators are considered. In acute pancreatitis in the blood, there was an increase in the indicators of total amylase, lipase, alkaline phosphatase, ALT, AST, and a decrease in the indicators of total protein and cholesterol. With pancreatitis in experimental animals, the rheological parameters of blood changed, the viscosity increased, the blood clotting time was shortened, the number of blood platelets increased, which worsened the fluidity of both blood and lymph and showed the phenomenon of a chronic inflammatory process. In pancreatitis, changes in the ionic composition of blood, lymph, and urine are noted. A decrease in Na+, K+, Ca+2 in blood and urine, a decrease in K+, Ca+2 in lymph, and an increase in Na+ indicate changes in ion exchange in the body. With a violation of the pancreas, characterized by a lack of cell activity in it, there is a violation of the balance system, cellular and humoral components of the blood, accompanied by changes in metabolism and the presence of endogenous poisoning. The circulatory system consists in maintaining the stability of the body in the environment during the destruction of internal organs and tissues. There was a blood clot in the small blood vessels of the pancreas, which in the future will lead to a violation of the blood supply to the microcirculatory core of the pancreas. The rate of blood flow in the trunk vein in acute pancreatitis decreased compared to the control group. The resistance Index RI in the trunk root decreased by 35% due to the fact that it is accompanied by an increase in the diameter of the trunk root. In acute pancreatitis, an increase in the rate of blood flow in the upper secondary artery was recorded, and in the case of posture, the rate of blood flow was 28±0.02 cm/s. As a result of a decrease in the tone of blood vessels after pancreatic disorders, the blood supply to the abdominal cavity and pancreas decreased. As a result of a decrease in the functional properties of the arteries and veins, which led to a decrease in blood flow in the pancreas, which, in turn, is manifested as a result of the preservation of microcirculatory disorders.