Abstract

Background. In view of the changes in the pathogenetic vector towards the study of comorbidity, searching for the ways of cardiovascular risk reduction is still relevant nowadays in specific subgroups of patients with moderate, unusual or undetectable risk levels (for example, in patients with accompanying acute surgical diseases of the abdominal cavity) Aim. Evaluation of arterial blood pressure indices in patients with acute calculous cholecystitis. Material and methods. The main group consisted of patients with acute calculous cholecystitis who underwent urgent cholecystectomy and were administered cardioprotective therapy (acetylsalicylic acid and atorvastatin). The first comparison group was formed from patients who underwent urgent cholecystectomy, but did not received cardioprotective therapy. The second comparison group was formed from patients who received cardioprotective therapy, but did not undergo cholecystectomy. Results and discussion. As a result of the study, the prevalence of patients with arterial hypertension (HTN) in the cohort was revealed. 72% of in-patients had elevated blood pressure (BP) on admission to the surgical department. Despite the positive results on the HTN control at the inpatient stage, the second follow-up revealed hypertensive BP profiles in most patients in the late postoperative period. The analysis of hospitalizations for acute coronary syndrome (ACS) in the late postoperative period also revealed the predominance of hypertensive blood pressure profiles in patients in all study groups. Conclusion. Development of ACS emerged in circumstances of poor HTN control.

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