Abstract

Purpose: In this study is to examine changes in metabolic risk factors (TC, TG, LDL-C, HDL-C, BMI, fasting blood glucose, fasting insulin and HOMA-IR) and Myokines (Irisin and FGF-21) according to exercise intensity through long-term aerobic exercise for obese men.BR Method: Subjects of the study calculated individual VO2max by exercise load test, A: low-intensity aerobic exercise group, VO2R 40% (low-intensity exercise group; LIEG), B: medium-intensity aerobic exercise group, VO2 60% (middle-intensity exercise group; MIEG), C: high-intensity aerobic exercise group, VO2R 80% (high-intensity exercise group; HIEG), D: control group (CG). For aerobic exercise, the treadmill speed was adjusted to maintain about ±3 of the target heart rate until the time spent 300kcal at the corresponding exercise intensity with the individual target heart rate by wearing a wireless heart rate device. In consideration of exercise adaptability, exercise time and intensity were recalculated after 6 weeks and applied for 12 weeks, 3 times a week.BR Results: TG, LDL-C, HDL-C, BMI, Glucose, Insulin, and HOMA-IR showed significant decreases in LEDG and HIEG, excluding TC. In MIEG of exercise treatment, the duration of exercise treatment showed a greater reduction after 12 weeks than after 6 weeks. In addition, changes in Irisin and FGF-21 also showed the most effective increase in MIEG, and the improvement of myokine was higher after 12 weeks of aerobic exercise.BR Conclusion: Even with the same exercise in the exercise metabolism of obese people, 12 weeks of moderate-intensity aerobic exercise is considered the most effective exercise treatment for myokine expression and lipid relief by accelerating the change of metabolic risk factors and the browning of white fat.

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