Abstract
In this paper we compared the information decomposition (ID) method and the spectral-statistical (SS) approach. We showed that the SS approach does not take into account the effect of small samples, and it does erroneous search of statistically significant period in the DNA sequence. Detection of the profile by SS approach depends solely on the ratio of the lengths of the latent periods. The revealed drawbacks of the spectral-statistical approach show that to search for DNA regions with latent periodicity it is more consistent from mathematical point of view to use Z-statistic and the method of information decomposition.
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