Процесс автоматизации неонатального скрининга путем интеграции с лабораторным оборудованием Victor Perkin Elmer

Abstract

This work aims to automate neonatal screening by integrating with Victor Perkin Elmer 1420 laboratory analyzer. Neonatal screening examines newborns to detect hereditary diseases for their further diagnosis and treatment. Screening helps prevent the development of severe conditions, which subsequently may lead to disability of the child, and is one of the most effective ways to identify common congenital and hereditary diseases. The genetic screening system is recognized to meet international standards, and since 2017 Kazakhstan has been an official member of the International Neonatal Screening Organization in the European group of ISNS. The automation of neonatal screening will eliminate the influence of subjective and human factors, as well as reduce the time of obtaining results and minimize human involvement in getting reliable information, which is achieved by automatic interpretation of the responses with the analyzer, with further transfer of data to the information system, where the construction of a grid of results occurs. The presented solution is introduced in industrial operation in 3 genetic laboratories in Almaty city (LLP «Center for molecular medicine»), Aktau city (RGP on PCV «Regional centre of mother and child» of Mangistau region), Ust-Kamenogorsk city («Regional centre of mother and child» of East Kazakhstan region)