Abstract
Purpose. To describe three clinical cases of corneal vascularization of different etiologies, to evaluate the possibilities of the method of optical coherence tomography of anterior segment in the mode of angiography (AS-OCTA) in diagnostic and selection of treatment strategies of corneal diseases, as well as to provide diagnostic protocol. Material and methods. For the first time AS-OCTА was performed at the S. Fyodorov Eye Microsurgery (Moscow). The presented clinical cases included three patients with different pathologies of the anterior segment of the eye: postherpetic neovascularization, superficial epithelial fibroplasia and limbal stem cell deficiency syndrome (LSCD). The scan was performed on an Avanti xR optical coherence tomography device (Optovue Inc. Fremont, California, USA) in the «OCT» and «Angio OCT» modes using the AngioVue program and the SSADA algorithm. Results. In the presented clinical cases, the use of AS-OCTA makes possible to accurately assess the depth, area and architectonics of the vessels, and helps to determine the tactics of surgical treatment and type of keratoplasty. However, the disadvantages of this technique include the complexity and long time required for its implementation, as well as the appearance of a large number of artifacts even with minimal eye movement of patients. At the same time, in the presence of a qualified operator and with proper compliance with the patient, it is possible to obtain valuable diagnostic data. Conclusion. Our study is the first in the Russian Federation to demonstrate the use of anterior segment OCT angiography to visualize the corneal vasculature and provide a protocol for performing it on an Avanti xR optical coherence tomograph. In this preliminary study of patients with corneal neovascularization, we regard the results obtained using AS-OCTA as promising for non-invasive vascular imaging, in particular, before and after the treatment of various conditions with corneal neovascularization. Key words: cornea, neovascularization, limbal stem cell deficiency, anterior segment optical coherence tomography, angiography, corneal limbal vasculature
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
