Современные взгляды на этиопатогенез инфаркта миокарда при сахарном диабете 2 типа и методы лечения (обзор литературы)

Abstract

This paper is devoted to an actual problem in cardiology and endocrinology, a problem of combined interaction of myocardial infarction and diabetes mellitus, which represent a serious medical and social significance. It is noted that fatal myocardial infarction in patients with diabetes mellitus is significantly higher than in patients without diabetes, regardless of the time of follow-up period. The authors note the importance of improvement the efficiency of complex treatment of acute myocardial infarction by correction of metabolic, blood rheological and microcirculatory parameters in patients with diabetes mellitus in combination with the total myocardial revascularization. This article highlights the epidemiology of diabetes mellitus, pathogenesis of myocardial infarction in patients with diabetes mellitus. The authors represent modern ideas of microcirculation disorders and pathophysiology of atherosclerosis and diabetes mellitus. Based on the pathophysiological model of diabetes, the authors reflect current approaches to the treatment of acute myocardial infarction. In con-clusion, the authors emphasize the need for an integrated approach to optimize the treatment algorithms and prognosis of myocardial infarction in patients with diabetes mellitus, to improve the nearest and long-term re-sults of percutaneous coronary intervention and coronary artery bypass grafting by the correction of metabolic disorders, blood rheology and lipid peroxidation.