Abstract
The observed dramatic 6–60-fold increase in fibrin degradation product levels in the cSDH cavity compared to peripheral blood was the rationale that underpinned the development of new concept for treatment of chronic subdural hematoma. The minimally invasive surgery results are reported, demonstrating decrease in fatality rate from 12–18% to 1.2% compared to craniotomy, as well as disappearance of severe post-operative complications, such as cerebral collapse. According to 1–10-year follow-up data, 91.7% of patients have shown good recovery.
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