Abstract

Diabetic macular edema (DME) is a pathological accumulation of fluid in the subretinal or intraretinal spaces of the macular area in patients with diabetic retinopathy and leads to a significant decrease in Central vision. Various types of technical equipment for retinal imaging have led to significant advances in the study of diabetic macular edema. In particular, optical coherence tomography (OCT) can provide linear and structural analysis of macular layers in great detail. The important role of inflammation in the development of changes in the macular region, based on OCT classification, associated with characteristic changes in the retina, has been studied. In this review, we will describe the pathogenesis of diabetic macular edema and discuss its types based on the results of OCT and identify the relationship of various types of (DME) with inflammation. Inflammation plays an important role in the pathogenesis of diabetic macular edema, but its role differs depending on the type of changes detected on OCT.

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