ВЛИЯНИЕ ПОКАЗАТЕЛЕЙ ВДЫХАЕМОГО ВОЗДУХА НА ТЕЧЕНИЕ БРОНХООБСТРУКТИВНОГО СИНДРОМА У ДЕТЕЙ

Abstract

Recent studies have made it possible to establish diverse pathogenetic mechanisms involved in the development of broncho-obstructive syndrome in children. Nevertheless, the role of microclimate indicators in the pathogenesis of the disease is still not fully understood. The purpose of this research was to assess the effect of inhaled air properties on the course of broncho-obstructive syndrome in children. 100 patients with acute obstructive bronchitis were examined, who were divided into 2 groups of 50/each depending on the use of Air Purifier by GREE Electric Appliances, Inc. (China). There was a decrease in the concentrations of PM2.5 particles, PM10 was 3.5 and 4 times lower in patients in whose wards the hardware air purification was carried out compared to the patients without the use of air purification (P<0.001). The level of Formaldehyde (CH2O) and volatile organic compounds (TVOCs) in the air was also significantly lower: by 1.9 and 1.8 times, respectively, in the air of the wards of patients who underwent air purification (P<0.001). The air quality index (AQI) was reduced almost trice the average value of which was observed in the favorable zone (<25), which was significantly less compared to G2 patients (P<0.001). As a result of improved indicators of inhaled air, the recovery of patients was accelerated, therefore the normalization of the general condition, elimination of respiratory failure, reduction of cough and hospitalization duration in patients of G1 had been achieved faster compared to the patients of G2 (P<0.01). Thus, the conducted study showed high prospects in studying of the positive effect of optimal microclimate on the course of acute obstructive bronchitis. Keywords: broncho-obstructive syndrome, children, acute obstructive bronchitis, microclimate, air purification, repeated episodes, prevention.