Abstract
Purpose – to assess the significance of retinal microcirculation disorders in progression of glaucomatous optic neuropathy (GON). Material and methods. In this 2-year prospective study 85 patients (124 eyes) the vessel density of the superficial parafoveal plexus (VD parafovea) and peripapillary retina (VD ppr) were measured with optical coherence tomography angiography, peripheral resistance index (RI) and blood flow velocity of the posterior short ciliary arteries (PSCA) and the central retinal artery (CRA) were studied by color Doppler flow mapping method. The predictor properties of each indicator were calculated from the area under the ROC curve (AUC). Results. The results of the study revealed a high significance of the values of relative density of the superficial plexus vessels in the parafoveolar region (VD parafovea AUC 0.70 ± 0.07), and the relative density of the microvasculature of the optic nerve head (ONH) and peripapillary retina (VD ppr 0.715 ± 0.07) as predictors of the progression of GON. Keywords: primary open-angle glaucoma, glaucomatous optic neuropathy, ocular blood flow, optical coherence tomography angiography
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