Abstract
The article presents a clinical case of systemic scleroderma and polymyositis in a young female patient. Notable is a rather rapid development of symptoms beginning with Raynaud’s syndrome, scleroderma skin lesion, and visceral pathology against the background of immunologic activity. Along with this, there were signs of polymyositis: weakness of proximal muscle groups, high indices of muscle enzymes, and positive electromyographic data. After SARS-CoV-2 vaccination, the patient noted a worsening of her general condition, increased muscle weakness and the appearance of new symptoms such as dysphagia, dysphonia, enlarged cervical lymph nodes, shortness of breath, and cough. The examination revealed vocal fold paralysis, paresis of the right side of the larynx and soft palate, and pulmonary hypertension. The results of the examination of the muscular component implied a primary muscular lesion.
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