Abstract
Purpose: This study was to identify the impact of symptom clusters, spiritual well-being on the quality of life in patients undergoing hemodialysis. Methods: Data were collected from 154 patients at six hemodialysis clinics from June 1<sup>st</sup>, 2016 to February 28<sup>th</sup>, 2017. The data were analyzed using factor analysis, multiple regression analysis. Results: The most frequently reported symptoms included fatigue, itching, dry skin, decreased interest in sex, difficulty falling asleep. The mean spiritual well-being score was 3.37. Factor analysis showed that eight distinct symptom clusters were identified: Emotional distress cluster, pain-fatigue cluster, skin disorder cluster, sleep disturbance related cluster, gastrointestinal-leg distress cluster, sexual distress cluster, nausea-vomiting cluster, shortness of breath-diarrhea cluster. The factor that most affected the quality of life was existential spiritual well-being. Conclusion: The finding supported existence of the symptom cluster and existential spiritual well-being affected the quality of life of hemodialysis patients. It was existential spiritual well-being, which showed 67.5% of explanatory power. It is necessary to manage on the characteristics of each dialysis patient’s symptoms cluster and to develop a strategy that can improve spiritual well-being.
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