Імунологічний статус пацієнтів із переломами щелеп на тлі генералізованого пародонтиту

Abstract

Prevention, diagnosis and treatment of lesions of the maxillofacial area is one of the most urgent modern medical and social problems, the signifi cance of which is determined by the constant increase in the frequency of maxillofacial injuries, which averages from 6.0 to 16.4 % of all traumas of peacetime.The aim of the study – to learn the individual immunological parameters in patients with fractures of the jaws against the background of generalized periodontitis.Materials and Methods. The article presents the analysis of individual parameters of cellular factors (phagocytic index, phagocytic count, phagocytosis completeness, NK-cells) and humoral immunity (total protein, globulin fractions, albumin, C-reactive protein, titre of lysozyme, immunoglobulins A, G, M) in serum in patients with jaw fractures on the background of generalized periodontitis (GP) (group A) and in patients with traumatic jaw lesions without periodontal tissue pathology (group B). The obtained values were compared with the data of the average norm.Results and Discussion. Investigation of changes in cellular factors of congenital immunity was performed in 45 patients with fractures of the jaws against the background of generalized periodontitis II-III stages (group A) and 41 patients with jaw fractures without concomitant periodontal pathology (group B). The obtained results were compared with the data of the average norm. The obtained results were processed statistically.Conclusions. As a result of the studies of the main parts of non-specifi c immunity in patients with jaw fractures, certain violations of humoral and cellular factors, which manifested themselves both in decreasing and dangerous increase of most of the studied parameters, were found, and in the patients with traumatic jaw lesions on the background of GP this tendency was worn more pronounced character.