골 생체조직공학을 위한 복합 세라믹 골 지지체의 제조와 생체역학적 특성

Abstract

Novel porous composite ceramic bone scaffolds composed of biodegradable PHBV(polyhydroxybutyrate-co-hydroxyvalerate) and TA(toothapatite) have been fabricated for bone tissue engineering by a modified solvent casting and particulate leach-ing method with salt-contained heat compression technique. The results of this study suggest that the PHBV-TA composite scaffold, especially the scaffold containing 30 weight of TA may be a good candidate far bone tissue engineering of non-load bearing area in oral and maxillofacial region.