Abstract
Diseases of cattle, accompanied by abortions, proceed as mixed infections. They are caused by viral and bacterial agents or a combination of both. To develop an effective method for diagnosing and treating intrauterine infection in farm animals, it is necessary to create a biological model. In the course of experimental work, we developed an original method of intrauterine infection of pregnant rabbits using a daily culture of E. coli at a concentration of 1 billion/ml, which was injected through the cervical canal using a classic milk catheter connected through an adapter to a disposable syringe. All manipulations were performed under ultrasound guidance. A technique has been developed that, based on the determination of the amount of nitrites and NO2 – + RNO in plasma, can be used to diagnose intrauterine pathologies and monitor their treatment.
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