Abstract
The authors have established the influence of adrenaline on the structure and mechanical properties of the surface of human lymphocytes and lymphocytes from patients with chronic leukemia. With the method of atomic force microscopy, the authors have revealed that under the influence of adrenaline there is a difference in the topography of lymphocytes’ surface in both groups. Under the influence of adrenalin load the surface of lymphocytes in healthy donors becomes roughened, but the lymphocytes’ surface in patients with chronic leukemia is ruffled. At the same time, adrenaline decreases elastic properties of cells. The effects of adrenalin load on the cell identified in the study are imortant for understanding of the pathogenesis of the functional status accompanied by a change in the microrheological properties of blood.
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