Значение гемодинамических расстройств в сосудах сетчатки в течении идиопатических ретиноваскулитов

Abstract

Relevance of this pathology is since both eyes are affected, characterized by a sluggish, relapsing course, affecting children and adolescents. Since this pathology is based on aseptic inflammation of the vascular wall in the retina of autoimmune origin, leading to hemodynamic disorders, our goal is to study the significance of hemodynamic disorders in various ocular fundus changes in patients with idiopathic retinovasculitis. Special research methods have been performed: autoperimetry, biomicroscopy of the anterior segment and internal structures of the eye, direct and reverse ophthalmoscopy, OCT of optic disc and yellow spot, autofluorescence vascular OCT with central retinal artery and central retinal vein calibrometry, ultrasound Doppler sonography of retinal vessels. Blood tests for antibodies of viral, bacterial and infectious diseases, immune status testing. Results: greater increase in the linear velocity of blood flow in the arteria ophthalmica, central retinal artery and central retinal vein and superior orbital vein in patients with neuroretinopathy: respectively: 64.86±0.46 cm/sec, 62.0±1.03 cm/sec (P<0.01), 21.0±0.7 cm/sec, 20.0±0.76 cm/sec (P<0.05). Angiospasm phenomena prevailed in all patients — RI=0.83±0.010; RI=0.8±0.014 (P<0.05). There were detected venous discirculation in the venous system with increase of linear velocity of blood flow up to 13,5±0,7 cm/sec and 15,0±0,74 cm/sec (P<0,05). In patients with maculodystrophy it was 10.8±0.82 cm/sec and 12.6±0.58 cm/sec (P<0.05). The frequency of hemodynamic disturbances prevailed in neuroretinopathies — 53.1% in arteria ophthalmica, 50% in central retinal artery, 50% in central retinal vein and 39% in superior orbital vein. Conclusion: The major disorders of microcirculation in the retinal arterio-venous system were detected in patients with neuroretinopathies. Microcirculatory disorders detected by ultrasound in patients with idiopathic retinovasculitis allow to determine the tactics, prognosis, and effectiveness of treatment.