Защитное действие вакцинации против кори, краснухи и паротита в отношении COVID-19

Abstract

Based on the results of studies, it has been shown that vaccination against measles, mumps rubella (MMR) can prevent mortality and severe forms of COVID-19 in vulnerable groups of the population. It was found that the high level of vaccination coverage against MMR was inversely correlated with the mortality rate from COVID-19 – the higher the vaccination rate against MMR, the lower the number of mortality from COVID-19 and severe forms. The effect of MMR immunization on the incidence of COVID-19 is explained by correspondence between COVID-19 virus proteins and MMR viruses. The results of studies conducted in various countries and have shown that the effect of protection against COVID-19 is based on the homology of individual sequences of SARS-CoV-2 coronavirus proteins with MMR viruses. The similarity of the SARS-COV-2 virus with the MMR viruses allows the MMR vaccine to be used for mass use for non-specific protection against COVID-19. In order to increase the effectiveness of vaccination against MMR in people with impaired health, the use of immunomodulatory drugs is recommended. This approach not only increases specific immunity against vaccinated infections, but also enhances nonspecific protection against COVID-19. Key words: SARS-CoV-2 virus, live vaccines, COVID-19 disease, immunization, measles, rubella, mumps