Abstract
<span class="a"><span lang="EN-US">the literature data about research and methods of mucoadhesive tablets have presented. The examples of compositions of active ingredients with excipients are given for implemented in pharmaceutical manufacturing drugs. Selection of these excipients shall provide tablets mucoadhesive properties.</span></span>
Highlights
Êîíöåíòðàö3ÿ â ìåæàõ 12,5 % ìîæå ìàòè ï3äâèùåíèé ïîòåíö3àë á3îàäãåç3¿; â) äëÿ äîñÿãíåííÿ êðàùî¿ àäãåç3¿ ïîë3ìåðíèé ëàíöþã ïîâèíåí ìàòè çíà÷íèé ñòóï3íü ãíó÷êîñò3, ÿêà çàëåæèòü â3ä âÿçêîñò3 3 êîåô3ö3oíòà äèôóç3¿; ã) ïîë3ìåðíèé íàáðÿê âïëèâào íà ìóêîàäãåçèâíó ì3öí3ñòü ïîë3ìåðíîãî êîìïîíåíòà
Ñþäè æ â3äíîñÿòü ñóáë3íãâàëüí3 òà çàù3÷í3 (áóêàëüí3) òàáëåòêè, ÿê3 ÿâëÿþòü ñîáîþ òâåðä3 îäíîäîçîâ3 ë3êàðñüê3 çàñîáè äëÿ çàñòîñóâàííÿ ï3ä ÿçèêîì àáî â ïîðîæíèí3 çà ùîêîþ, â3äïîâ3äíî, äëÿ îäåðæàííÿ ñèñòåìíî¿ ä3¿
Summary
Ìóêîàäãåç3éí3 òàáëåòêè: õàðàêòåðèñòèêà ë3êàðñüêî¿ ôîðìè, âèìîãè, ï3äõîäè äî ðîçðîáêè, äîñë3äæåííÿ òàáëåòîê, ï3äá3ð äîïîì3æíèõ ðå÷îâèí Ñåðåä ð3çíèõ ì3ñöü äîñòàâêè ë3ê3â ÷åðåç ñëèçîâó îáîëîíêó áóëî âèÿâëåíî, ùî ñëèçîâà îáîëîíêà ïîðîæíèíè ðîòà o íàéá3ëüø çðó÷íîþ òà ëåãêî äîñòóïíîþ äëÿ ì3ñöåâî¿ 3 ñèñòåìíî¿ äîñòàâêè ë3ê3â [1]. Ó ðîòîâ3é ïîðîæíèí3 âñìîêòóâàííÿ ë3ê3â ìîæå çä3éñíþâàòèñÿ øëÿõîì ñóáë3íãâàëüíî¿ (ï3äÿçèêîâà), áóêàëüíî¿ (ù3÷íà) àáî ì3ñöåâî¿ äîñòàâêè.
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