Abstract

The article presents research results obtained during the development of a new treatment for highly productive cows with acute postpartum endometritis, which was performed at the Department of obstetrics, surgery and physiology of domestic animals the Don State Agrarian University in Persianovka settlement Oktyabrsky district, Rostov region. It was found that once in the affected cavity, the finished drug is completely absorbed and has a General and local effect on the affected tissues and organs. Animals of the first group were injected with the created enzyme – based drug at the following ratio of components, wt.%: dioxidin – 30.0, iodopovidone – 2.0 g, alantoin – 10.0 g, aloe extract – 5.0, retinol palmitate – 30.0 (300,000 IU), tocopherol acetate – 8.0 (120 mg), trypsin (20 thousand u), chymotrypsin (20 thousand u), rennin (20 thousand u) propranolol – 10.0, glycerin – 5,0, vaseline oil (base) - 42 ml. Animals of the second group were given a ready-made veterinary drug "Nioxitil" with the composition: oxytetracycline, tylosin tartrate, nitroxoline. To compare the therapeutic effectiveness of the proposed drug with the already approved drug, 2 groups of animals with 10 heads were formed on the principle of analogous pairs with postpartum endometritis. When using the test drug, the improvement of the General and local condition of the animal occurred on the 6th day from the start of the drug, the General therapeutic course was 11 days. The high therapeutic effectiveness of the experimental drug was noted.

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