Анализ кардиоваскулярных и кардиометаболических рисков при ассоциации бронхиальной астмы и ожирения

Abstract

Bronchial asthma and obesity are showing a steady increase in incidence worldwide, incurring significant economic losses for society. There is no doubt about the pathogenetic role of obesity in the development of cardiovascular events. The purpose is to analyze the current data that demonstrate the impact of asthma and obesity association on the increased risk of cardiovascular disease. The critical role of obesity is noted as a risk factor for the development and progression of both bronchial asthma and cardiovascular diseases. The review emphasizes importance of determining cardiovascular and cardiometabolic risks according to generally accepted scales specified in clinical guidelines. As part of the review, the combination of bronchial asthma and cardiovascular diseases was analyzed, and their etiopathogenetic interdependence was noted. The role of metabolic processes in adipose tissue is shown, which can increase both inflammation in bronchial asthma and lead to the progression of cardiovascular diseases. Understanding the mechanisms of mutual influence will allow for personalized treatment, as well as the prevention of cardiovascular accidents in patients with bronchial asthma and obesity.