ВЛИЯНИЕ АЛЛЕРГИЧЕСКИХ ФАКТОРОВ НА УРОВЕНЬ ОБЩЕГО ИММУНОГЛОБУЛИНА Е В СЫВОРОТКЕ КРОВИ

Abstract

The correct diagnosis of allergic diseases at the early stages is important nowadays, despite the growing importance of infectious pathology. The basic tests for allergy diagnosis are the determination of the level of total serum and specific immunoglobulins E (Ig E), as a key link in the development of type1 allergic reaction. Allergic factors affecting the level of Ig E include the nature and degree of sensitization of patients to one or more groups of allergens. The study included 143 patients, of which 104 patients with atopy were divided into allergic asthma+ allergic rhinitis patient’s group (58 patients) and group of 46 patients who had just allergic rhinitis. 39 healthy volunteers were the control group. The groups were matching by gender and age. The study evaluated the influence of allergic factors on the level of total Ig E in patients with allergic diseases. Higher values of Ig E total were obtained in patients with allergic asthma and polysensitization. About half of patients with rhinitis and 15% of patients with asthma have normal total Ig E level, that is one of the reasons to change approaches to normal values of this allergy marker.