СОСТОЯНИЕ ИММУНИТЕТА У КОРОВ ПРИ ПОСЛЕРОДОВОМ ЭНДОМЕТРИТЕ В ХОЗЯЙСТВАХ ПРИМОРСКОГО КРАЯ

Abstract

The objective of the research was to study the state of immunity in healthy and endometritic cows on farms in the Primorsky Krai of the Russian Federation. It was established that when studying the absolute and relative number of lymphocytes in sick and healthy cows, the total number of lymphocytes in the postpartum period did not significantly differ and did not change during all study periods, it was within 5.16-6.1 109/l. The number of T and B lymphocytes in healthy cows was significantly higher in all study periods than in cows with endometritis. In patients with postpartum endometritis (the initial stage of body disease, the concentration of class G immunoglobulins on the first day after delivery was by 13.7% lower than in healthy animals, by day 7 it decreased by 25.9%, by day 14 – by 32.7%, by day 28 – increased by 26.7%. The concentration of immunoglobulins M in sick animals on the first day was by 18.5% lower than in healthy animals, on the 7th day – by 30.1%, on the 14th day – by 25.8%, on the day 28 – by 20.83%. When studying non-specific cellular (phagocytic activity of neutrophils) and humoral (bactericidal and lysozyme activity of blood serum), a significantly increased phagocytic activity of leukocytes in healthy animals was established, as compared to sick animals, but the phagocytic number was higher in sick animals. The amount of lysozyme in the serum of healthy animals was at a high level) and the bactericidal activity of serum during all study periods.