Abstract
The paper presents a brief survey of the IBMP-based studies with participation of test-subjects volunteered for isolation in closed chambers and mockups of space vehicles reproducing various factors and situations attending space missions. The authors outline the primary findings pertaining to effects of the multitude of isolation factors on human psychophysiology, physiology, biochemistry, immunology and microbiology. The obtained facts witness that there is good reason to pursue studies of the effects of confinement and controlled environment in the interests of medical support to crews on space missions beyond low-Earth orbits.
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