Abstract

Purpose. Optimization of medical care for women in menopause with dry eye syndrome from the standpoint of experimental and clinical substantiation of combined technologies. Material and methods. The studies were carried out on a group of 72 patients (144 eyes) in the postmenopausal period with dry eye syndrome. The average age of women was 54.4±3.3 years. All patients, depending on the therapy, were divided into two groups. The first group (control) consisted of 34 women (68 eyes) who received only local daily monotherapy for 20 days – instillation of low-viscosity «artificial tear» preparations HyloComod. Patients of the main group were divided into 2 subgroups and used a combined treatment technology. The first subgroup consisted of 21 patients (42 eyes), who, in addition to local daily therapy of the above drug, received a suis-organ complex preparation of estrogen-like orientation Ovarium compositum once every 3 months. The second subgroup included 17 patients (34 eyes) who received a treatment technology that included local daily therapy with artificial tears in combination with courses (once every 3 months) of exposure to the head area by a pulsed low-frequency electromagnetic field in combination with suis-organ complex preparation of estrogen-like orientation Ovarium compositum. Results. The combined treatment technology was well tolerated in all examined women. There were no complications or side effects. A significant increase in the main tear production in women of the main group made it possible to achieve a significantly more pronounced decrease in symptoms of subjective discomfort than in women in the control group. The achieved results of treatment of women in the main group persisted for 2.5–3 months, which determined the frequency of the courses of combination therapy with a frequency of twice every 6 months during the subsequent observation period. Conclusion. The course of combined therapy makes it possible to achieve significant relief of subjective manifestations of dry eye syndrome in postmenopausal women. The implementation of the therapeutic effect occurs, apparently, due to the synergism of the natural factors used, which makes it possible to significantly activate the compensatory and adaptive processes in the meibomian glands. Key words: dry eye syndrome of climacteric origin, combined treatment technology, estrogen deficiency, sex hormones.

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