ОСОБЕННОСТИ ТЕЧЕНИЯ И ИСХОДЫ ОСТРЫХ НАРУШЕНИЙ МОЗГОВОГО КРОВООБРАЩЕНИЯ У ПАЦИЕНТОВ С COVID-19

Abstract

The article presents the clinical features, course and immediate outcomes of cerebral strokes in 612 patients with acute cerebrovascular accident during the COVID-19 pandemic. Patients were divided into two groups – the main group (persons with acute cerebrovascular accident and COVID-19, n = 306) and the control group (patients with stroke, n = 306). It was found that in patients with stroke and a new coronavirus infection, compared with the control group, there are certain gender and age differences. Patients of both groups premorbidly had risk factors for the development of stroke – arterial hypertension, hyperglycemia, arrhythmias, dyslipidemia and, accordingly, high risks of developing extracerebral complications and adverse outcomes of the disease. In patients with stroke and COVID-19, severe and extremely severe neurological disorders prevailed (31.7 % and 38.9 %, respectively), hemispheric localization of brain lesions prevailed over stem and cerebellar lesions, and the course of the disease in 60.1 % of cases was complicated by the development of polysegmental pneumonia with a predominance of moderate (34.2 %), severe (29.4 %) and critical (21.2 %) lesions. To check the equality of the mean values in the two samples, the standardization method was used using Student's t-test. These features had a negative impact on the outcomes of the disease, which was manifested by an increase in mortality in the main group of patients by 2.2 times compared with the control group