ПРИМЕНЕНИЕ МЕТОДА УЛЬТРАЗВУКОВОЙ ОСТЕОМЕТРИИ ДЛЯ СКРИНИНГ-ДИАГНОСТИКИ И МОНИТОРИНГА ЭФФЕКТИВНОСТИ ТЕРАПИИ ОСТЕОПОРОЗА

Abstract

Purpose: Development of an algorithm screening diagnostics of osteoporosis with use of ultrasonic osteometers based on complex data analysis of external instrumental investigations and the anamnesis data. Material and methods: The material including data of complex researches of 53 women aged from 20 up to 75 years, such as results of external inspection and anamnesis and data of instrumental researches was used: ultrasonic osteometry of a calcaneal bone and two energy x-ray densitometry inspection of lumbar area. Results: The developed complex processing procedure of data based on data of external inspection, the anamnesis and an ultrasonic osteometry leads to the acceptable level of false-negative and false positive errors of diagnostics when comparing with data of x-ray two-energy densitometry. Conclusions: The comparative analysis of accuracy of assessment of patient’s distribution on risk groups based on data of external inspection and the anamnesis with data densitometry is carried out. The comparative analysis of accuracy on risk groups based on data of an ultrasonic osteometry with data densitometry is carried out. It was shown that the level of errors when using these two tool techniques is rather high. The complex rule of creation of risk groups based on data of external inspection, the anamnesis and an ultrasonic osteometry which showed good correlation with data of measurements with use two-energy x-ray densitometry is developed. The conversion function given the received complex decisive rule in the T scale – parameter, compatible to the estimates received at two-energy x-ray densitometry is constructed.