Abstract
This study investigates the bioactivities of Hibiscus syriacus (H. syriacus) L. flower extracts on dermal cells and bacteria. The white and pink H. syriacus L. flower extracts showed no or minimal cytotoxicity on HaCaT (human keratinocyte) and B16F10 (mouse melanoma) cell lines. H. syriacus L. flower extract inhibited oxidative stress, and its effect was superior to the effect of glutathione. The antioxidant efficacy of pink H. syriacus L. flower extract was higher than the white flower extract. The chloroform layer of the white H. syriacus L. flower extract (40 μg/mL) inhibited melanin synthesis and showed remarkable antibacterial effects against Staphylococcus aureus. The extracted layer also exhibited antibacterial effects on Staphylococcus epidermidis and Pseudomonas aeruginosa. Based on the bioactivity experiment, the white H. syriacus L. flower extract was more effective than the pink flower extract in inhibiting melanin synthesis and antibacterial efficacy. The results of this study indicate potential applications of H. syriacus L. flowers in cosmetics.
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