Abstract
According to the data of a retrospective assessment of the medical histories of 238 patients, the features of the clinical course of pulmonary tuberculosis in patients with late-stage HIV infection and mental pathology in various morbid variants are considered in a comparative aspect. The data on age-sex and social characteristics, clinical, radiological and bacteriologicalfeatures of the course of the disease in the observed patients are presented. It was found that disseminated (39.4%) and generalized (24.5%) forms of the disease prevailed in patients with pulmonary tuberculosis and late-stage HIV infection in combination with mental illnesses. Bacterioexcretion was observed in 60.6% of patients, including 70.2% of patients with multidrug-resistant tuberculosis and 44.7% of patients with cavities. Distinctive clinical and radiological signs of the course of tuberculosis in patients with various comorbid variants of these nosologies are presented, which is essential for the development of patient-oriented management programs and improvement of treatment effectiveness in these severe categories of patients.
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