Применение клеток стромально-васкулярной фракции аутожировой ткани в хирургии повреждений плечевого сплетения

Abstract

The purpose — to evaluate the therapeutic properties of cells of the stromal vascular fraction isolated from adipose tissue of injuries of brachial plexus. Material and methods. The study was carried out on 62 patients using cells of the stromal vascular fraction and classical methods of treatment for brachial plexus injury. The efficiency of regeneration was assessed using electromyography and a positive recovery of motor and sensory functions. Results. Evaluation of the results of surgical treatment using cells of the stromal vascular fraction after neurolysis of the brachial plexus showed the restoration of early function of M3-M5 and S3–S4 in 90% of patients, and in the comparison group 68%. The number of patients with M4–M5 functions in the group with the use cells of the stromal vascular fraction for brachial plexus neurotization was 85%, while in the control group it was 64%. The ENMG study data also indicated an increase in the average number of motor units by 30% after the use of cells of the stromal vascular fraction, in contrast to the comparison group. Conclusion. Cells of the stromal vascular fraction from adipose tissue appear to be promising stimulators for the regeneration for recovery from trauma to the brachial plexus.