Abstract
There is a new principle of preparing diet for a patient with ulcerative colitis (UC). Within 4 years, we observed and comprehensively examined 60 patients UC who received standard treatment. In group 1(n=30) was used as a dietary therapy specific individual elimination hypoallergenic diet (ISEH diet), picked up in vitro and composed by exclusion from the diet of those products, which can be a source of food sensitization. To identify the immunopathological reactions I, III and IY types of food allergens used a range of methods - ELISA (IgE-specific) and the reaction of inhibition migration of leukocytes(RIML), modified by NN Matyshevа and LS Kositskаyа. Group 2(n = 30) received a standard mechanically and chemically sparing diet. Patients with UC showed a high degree of sensitization to food antigens. Usage of the ISEН diet promoted a more rapid onset and prolonged maintenance of clinical and endoscopic remission, more than in the standard diet group, without the use of corticosteroids and thiopurins, as well as a significant decrease in the number of disease relapses. Diet of patients with UC should be hypoallergenic. The best results are observed in the preparation of a diet based on a comprehensive individual screening-testing of food allergens using laboratory diagnostic methods based on cell-type reactions and methods for detecting specific antibodies to food antigens. Results of a 4- year follow-up for patients with UC show high efficacy ISEH diet in the treatment and maintaining remission of these patients.
Highlights
There is a new principle of preparing diet for a patient
which can be a source of food sensitization
IY types of food allergens used a range of methods
Summary
There is a new principle of preparing diet for a patient with ulcerative colitis (UC). Within 4 years, we observed and comprehensively examined 60 patients UC who received standard treatment. The best results are observed in the preparation of a diet based on a comprehensive individual screening-testing of food allergens using laboratory diagnostic methods based on cell-type reactions and methods for detecting specific antibodies to food antigens. У значительного числа больных воспалительных заболеваний кишечника (ВЗК) (от 35 до 75%) обострению заболевания предшествует нарушение базисной диеты, что делает вопросы питания при этих заболеваниях очень значимыми [1, 2]. (2006) отмечает, что в групповых диетах лечебного питания нередко используются аллергенные продукты, которые могут поддерживать патологический процесс в желудочно-кишечном тракте, в связи с чем рекомендуется более тщательно обследовать пациентов с гастроэнтерологическими заболеваниями и индивидуализировать их питание. Диеты исключения из рациона непереносимых пищевых продуктов позволяют достигать исключительно хороших клинических результатов [8]
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