Акушерська та перинатальна патологія в жінок з великими акушерськими синдромами в анамнезі

Abstract

Purpose - to determine the features of obstetric and perinatal pathology in women who had complications from the group of major obstetric syndromes (MOS) in the anamnesis during previous pregnancies. Materials and methods. A prospective analysis of the course of pregnancy, childbirth and the condition of newborns was conducted in 120 pregnant women who had complications from the group of MOS in the anamnesis during previous pregnancies and received generally accepted diagnostic and treatment-prophylactic measures during this pregnancy (during 2019-2022). Statistical processing of research results was performed using the standard programs Microsoft Excel 5.0 and Statistica 6.0. Results. Peculiarities of the course of pregnancy and childbirth in women with a history of MOS are characterized by a high frequency of the threat of premature birth - 32.5% of cases, which determines the high frequency of perinatal pathology. In addition, it is possible to note the high frequency of premature births - 10.8% of cases. Attention is drawn to the stable high rates of the following complications of the III trimester of pregnancy: gestational anemia in 29.2% of cases; preeclampsia 13.3% of cases; placental insufficiency with growth retardation syndrome in 14.2% of cases; and violation of microbiocinosis of the genital tract in 24.2% of cases; without a tendency to decrease the frequency of these complications over the years. The consequence of these complications is an increase in the frequency of cesarean sections to 30.1% of cases. Conclusions. The identified features of obstetric and perinatal pathology in pregnant women who had complications from the MOS group during previous pregnancies can serve as markers for predicting the risk of developing complications from the mother and the fetus in these pregnant women. In our opinion, further analysis of functional, instrumental and laboratory indicators in these women can provide an opportunity to identify the most informative prognostic criteria regarding the development of MOS, and will allow the development of an effective method of predicting obstetric and perinatal complications in these women. The research was carried out in accordance with the principles of the Declaration of Helsinki. The research protocol was approved by the Local Ethics Committee of the institution mentioned in the work. Women's informed consent was obtained for the study. No conflict of interests was declared by the author.