Імунологічний профіль крові ярок за використання у раціонах про- і пребіотичних добавок

Abstract

Goal. To study the effect of different doses of pro- and pre-biotic preparations of domestic production, made based on baker’s yeast Saccharomyces cerevisiae, when they are added to feeding rations of heifers, on the immunological status of the organism and the intensity of growth and development of animals. Methods. The study was conducted on heifers of Askanian meat-wool breeds aged from 11 to 12 months in the winter-spring stall period. The diet of animals in the control group consisted of meadow hay and standard mixed fodder K 83-19-89. Animals of the experimental groups in the mixed fodder received pro- and pre-biotic additions. The studies used zootechnical (determination of gross, average daily, and relative weight gain of animals), physiological and biochemical (determination of the number of leukocytes in the blood, the content of circulating immune complexes and lysozyme and bactericidal activity), analytical (analysis of literature sources on the topic of the article), and statistical computer programs in the processing the obtained data) methods. Results. It is established that the use in mixed fodder for heifers at the age of 11–12 months in the winter-spring stall period of the pro-biotic Enzymaktyv (EA) in doses of 0.4; 0.8 and 1.2% and pre-biotic Inactivated dry glutathione yeast (IDGY) in doses of 1.0, 1.4 and 1.8% by its weight has a positive effect on the level of immunological ingredients in the blood and productive qualities of animals. The addition of pro-biotic EA and pre-biotic IDGY in the specified doses to mixed fodder of heifers increases the number of leukocytes in their blood by 1.2–6.4%, reduces the content of medium molecular circulating immune complexes (CIC) in the blood by 5.3–12.8%, activates lysozyme and bactericidal activity in serum in 1.03–1.25 times. The use of pro-biotic EA in feed in the studied doses increases the gross increase in live weight of animals by 15–35%, and relative — by 14–32%, while the use of prebiotic IDGY — by 30–55 and 27–50% respectively. Conclusions. Taking into account the results of immunological parameters of blood and intensity of growth of animals, they recommend adding 0.8% pro-biotic EA and 1.4% pre-biotic IDGY to the feed for heifers in the winter-spring stall period.