Аналіз предикторів виникнення несприятливих серцево-судинних і цереброваскулярних подій після операції Бенталла

Abstract

The aim – to analyze the risk factors for the occurrence of major adverse cardiac and cardiovascular events in the early period after the Bentall procedure.Materials and methods. The study analyzed the medical records of adult patients (aged 18 to 75 years) who underwent Bentall procedure for ascending aortic aneurysm between 2012 and 2021. Univariate and multivariate analysis (logistic regression) were used to determine prognostic risk factors.Results and discussion. In patients with MACCE grade 3 hypertension was observed by 14.4 % (p = 0.048) more often, duration of cardiopulmonary bypass was by 14.1 % (p = 0.017) longer, the cross-clamping of the aorta duration was by 16.3 % (p = 0.039) longer, and the lactate level at the end of the surgery was by 23.6 % (p = 0.036) higher compared to patients without MACCE. Further multivariate logistic regression analysis established two main predictors of the development of MACCE in the early postoperative period – the presence of the 3rd degree arterial hypertension (OD 2.030 95 % CI 0.578–7.161, p = 0.018) and the duration of aortic clamping (OD 1.102 95 % CI 0.931–2.136, p = 0.018).Conclusions. The 3rd degree arterial hypertension and the duration of aortic clamping were independent predictors of the development of MACCE in the early postoperative period.