ИЗМЕНЕНИЯ КОГНИТИВНЫХ ВЫЗВАННЫХ ПОТЕНЦИАЛОВ И СПОНТАННОЙ БИОЭЛЕКТРИЧЕСКОЙ АКТИВНОСТИ В УСЛОВИЯХ НОРМОБАРИЧЕСКОЙ ГИПОКСИИ

Abstract

The latencies and amplitudes of auditory event related potentials (ERPs) in oddball paradigm were evaluated in men in the conditions of normoxia and influence of the moderate (11.5 % content of O2 in oxygen-nitrogen mix) normobaric hypoxia. Spectral power changes were evaluated in the same conditions and in the eyes closed states. There were obtained increase of spectral power in theta- (4—8 Hz) and beta-1 (13—18 Нz) EEG frequency bands in moderate hypoxia in eyes closed condition without cognitive task in comparison with normoxia states. There were no significant EEG spectral power changes in attention task performance in hypoxia compared to normoxia. Performance accuracy in attention task and the latencies of average ERP components were estimated. Difference waves were used to isolate the P3 wave. Increase of a latency of the P3 component in difference wave was observed in the condition of the moderate hypoxia, without the decrease of accuracy in task performance and P3 component amplitude changes. Thus, increase of the P3 wave latency of the auditory ERPs even without the changes of accuracy in task performance can serve as an index of hypoxia influence in the performance of the cognitive and attention tasks.