Abstract

Object. Vibration exposure is the most common adverse technogenic factor in the work and living conditions of many people. A significant impact on the state of the oral cavity have many socio-hygienic factors; the nature of their impact, their variability depends on the individual, the environmental situation in the region, the social conditions of people, as well as their professional activities. The undeniable fact is that production factors have an impact on both somatic health and dental status. These circumstances explain the importance of studying the development of the structure of dental rudiments, taking into account the mineral metabolism in the conditions of various anthropogenic influences, including the action of General industrial vibration.
 Purpose of the study. Explore features of the histogenesis of teeth based on mineral metabolism during vibrational excitation.
 Materials and methods. Wistar rats was performed with a vibration 9 to day 18 of pregnancy. We studied the morphology of the tooth germs in the fetus. Analytical studies of the mineral composition of the liver were performed by IRS-nuclear laboratory NGO "CBM" (Moscow) in the method of Dr. A.V. Skalniy. In the liver, the concentration female elements: Ca, Cd, Cu, Fe, Mg, P, Pb, Se, Zn.
 Results. The features in the structure of tooth germs and mineral metabolism in the mother-fetus system with vibrational excitation. Identified structural changes reveal a violation of microcirculation, the development of hypoxia in the tissues of the tooth germ and accelerated dentinogenesis. Change the concentration of minerals in the body - significantly reduces the concentration of essential elements of Ca, Fe, Mg and significantly increased the content of Cu, Cd, Pb.
 Conclusion. The observed changes in the morphology of tooth germs and mineral metabolism, are a reflection of altered homeostasis system the mother-fetus arising under the influence of vibration exposure.

Highlights

  • Так как минеральный состав тела является отражением процессов гомеостаза клеток, тканей и организма в целом, мы провели определение минерального обмена у экспериментальных животных в условиях вибрационного воздействия

  • Измерение слоя дентина показало увеличение его толщины в сравнении с контролем на 45%, кроме того, толщина дентина на его протяжении носит неравномерный характер

  • 5. Развитие зубных зачатков, минеральный обмен и состояние опорно-двигательного аппарата при действии вибрации / С

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Summary

Introduction

Для исследования использовали две группы плодов: от интактной беременности и от беременности в условиях вибрации. Так как минеральный состав тела является отражением процессов гомеостаза клеток, тканей и организма в целом, мы провели определение минерального обмена у экспериментальных животных в условиях вибрационного воздействия. Выбор печени в качестве исследуемого биосубстрата обусловлен тем, что она является одним из основных органов-депо для многих биоэлементов, обеспечивает процессы детоксикации и поддержания гомеостаза в организме самки, то есть участвует в регуляции важнейших процессов, в том числе и в период беременности [2, 4].

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