Abstract

Gorlin-Goltz syndrome is a rare hereditary disorder characterised by multiple congenital abnormalities and cancer predisposition – basal cell cancer (BCC) and medulloblastoma. BCC develops in most patients throughout their life. The number of BCCs varies from a few to several thousand. In this paper we describe the diagnostic features for Gorlin-Goltz syndrome and treatment options for BCC associated with this hereditary disease. We analysed our clinical experience and presented data on patients with multiple BCC related to Gorlin-Goltz syndrome who were referred to N.N. Blokhin National Medical Research Center of Oncology from 2012 to 2023 (n = 10)

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