КОМПЛЕКСНЫЙ ПОДХОД К ЛЕЧЕНИЮ БАКТЕРИАЛЬНОГО ВАГИНОЗА У ПАЦИЕНТОК С СИНДРОМОМ ПОЛИКИСТОЗНЫХ ЯИЧНИКОВ

Abstract

A two-stage complex method of therapy of bacterial vaginosis (BV) in 29 patients with polycystic ovary syndrome (PCOS) is proposed, consisting in the use of standard metronidazole therapy (vaginal suppositories of 500 mg 2 times a day for 7 days) at the first stage and therapy with Acylact DUO at the second stage (1 candle in the vagina per night of 10 days), effective in relieving clinical manifestations and preventing recurrence of vaginal dysbiosis. Intravaginal administration of metronidazole to patients with polycystic ovary syndrome (PCOS) and bacterial vaginosis (BV) significantly reduced the concentration of anaerobic microorganisms. The appointment with Acylact DUO stimulated the growth of its own lactobacilli and helped to reduce the number of relapses of the disease by increasing the protective properties in the vagina. Normalization of the vaginal microflora was noted in all patients included in the study. After three months, normal vaginal biocenosis was detected in 26 patients (89.6% of women) according to a control smear study to detect key cells as markers of bacterial vaginosis. Clinical manifestations of bacterial vaginosis (itching, burning, pathological discharge) were not detected in any patient. Thus, the conducted study showed high efficiency of complex two-stage treatment of bacterial vaginosis, consisting in the use of vaginal candles containing metronidazole at the first stage, followed by the drug Acylact DUO in patients with polycystic ovary syndrome, provided timely correction of hormonal and metabolic disorders in them.