Abstract
The purpose of the study is to define the role of immunoinflammatory reactions in predicting possible ACS development during hospital stay period. Matherial and methods. We studied the following biomarkers: C-reactive protein (hs-CRP), natriuretic peptide (NTproBNP), interleukin-6 (IL-6), interleukin-10 (IL-10) in the blood and IL-6, IL-10 in the saliva of the patients with acute coronary syndrome (ACS) (n=173) and stable angina (SA) (n=57) during 1—3 days of hospitalization. Results. There has been identified a high hs-CRР and IL-6 levels in the blood of the patients suffering from ACS in comparison with SA patients. A higher IL-10 values in the blood has been revealed in patients with unstable angina and non-Q myocardial infarction (non-Q MI), and NTproBNP — for patients with Q-wave myocardial infarction (QMI). Development of complications of ACS patients was preceded by a higher IL-6 and IL-10 in their saliva, in comparison with the blood. Conclusion. The obtained results could be used as supplementary diagnostic criteria, which allow to predict any development of cardiovascular complications throughout the hospital stay period of ACS patients.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
