АНАЛИЗ КОГОРТЫ И ЗАБОЛЕВАЕМОСТЬ ЛИЦ, ПОЛУЧИВШИХ ОБЛУЧЕНИЕ РАДИОАКТИВНЫМ ЙОДОМ ВО ВРЕМЯ ВНУТРИУТРОБНОГО РАЗВИТИЯ

Abstract

EXPOSED TO RADIOACTIVE IODINE DURING FETAL DEVELOP-MENT The purpose of this work was to study the incidence in children born and liv-ing in the territory of the Stolin district of the Brest region, irradiated in utero due to the incorporation of radioactive iodine (I-131), as a result of the Chernobyl ac-cident, compared with the health status of children who were born later and were not exposed to such irradiation. The study group included 123 individuals, the comparison group included 113 residents from the same area, identical in their status, but born in 1988. It has been established that the transplacental intake of radioactive iodine into the thyroid gland (TG) of the fetuses of pregnant women formed smaller absorbed doses than that of their mothers. Increased morbidity among those irradiated in utero was recorded immediately after the accident and remained at a higher level thereafter. In the control group, the incidence has stabi-lized after about 2000. An increase in the incidence of mental and behavioral dis-orders, diseases of the nervous system, circulatory system and diseases of the genitourinary system was recorded. The study of gender characteristics revealed more frequent changes in the health status of females. In this article, the data ob-tained are discussed from the point of view of the instability of specific genes of thyroid cells after the incorporation of I-131, which are capable of being respon-sible for the synthesis of thyroid hormones, which may be reflected in the subse-quent appearance of various pathologies.