Abstract

Assessment of the physiological and immunological status of fish is an urgent problem of modern aquaculture. One of the methods of such assessment is based on hematological and biochemical studies. Blood is the most sensitive and informative indicator of changes occurring in the body of fish. It reacts quickly and acutely to the effects of various adverse environmental factors and can serve as one of the early indicators of a violation of the functional state of fish. The study 
 of the effect of a probiotic drug on the enterosorbent “Florin forte” on hematological and biochemical blood parameters, in particular, on the level of hemoglobin, total serum protein, triglycerides, cholesterol, glucose, as well as on the distribution of shaped elements of peripheral blood of Bester (Huso huso × Acipenser ruthenus) was carried out on the basis of the Innovation Center “Bioaquapark – scientific andtechnical center of aquaculture” ASTU for 30 days. As a result of the conducted studies, it was noted that the use of the sorbed form of the probiotic drug has a positive effect on the physiological and immunological condition of the farmed fish. Thus, the blood of Bester's two-year-olds grown on compound feeds with the addition of probiotic enterosorbent was characterized by an increase in hemoglobin levels to 64.9 g/l, total whey protein to 23.6 g/l, as well as a decrease in cholesterol and glucose concentrations to 2.6 and 0.55 mmol/l, respectively. In the leukocyte formula of the studied fish, shifts in the quantitative ratios of leukocytes were found, confirming the body's reaction to the introduction of a probiotic drug on enterosorbent into the diet and considered as an adaptive mechanism that increases the protective function of the blood.

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